The Upper and Lower Respiratory Tracts Differ in Their Requirement of IFN- and IL-4 in Controlling Respiratory Mycoplasma Infection and Disease
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The upper and lower respiratory tracts differ in their requirement of IFN-gamma and IL-4 in controlling respiratory mycoplasma infection and disease.
The purpose of this study is to evaluate the significance of IFN-gamma and IL-4 production in controlling mycoplasma infection and the pathogenesis of disease in the upper and lower respiratory tract. By using IFN-gamma knockout and IL-4 knockout BALB/c mice, we were able to study the contribution of these cytokines in the development of pathogenesis and/or protection in response to mycoplasma ...
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تاریخ انتشار 2004